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Ipratropium bromide (Atrovent®)

Class: Topical Anticholinergic/Parasympatholytic
Route: Inhalation

Adult Dose:

  • Standing order - 0.5 mg mixed with 2.5 mg albuterol given via nebulizer over 5-15 minutes if the patient is not improving after a single albuterol-only nebulized treatment.
  • A second 0.5 mg dose mixed with 2.5 mg albuterol may be given standing order, if needed.
  • May be mixed with each of the three albuterol doses for status asthmaticus
  • BioTel must authorize any additional doses.
Pediatric Dose:

If less than 1 year old, standing order

  • 0.25 mg mixed with 2.5 mg albuterol given via nebulizer over 5 - 15 minutes if the patient is not improving after a single albuterol-only nebulized treatment.
  • Medics may administer a second and third dose of 0.25 mg ipratropium mixed with 2.5 mg albuterol.
  • If status asthmaticus is present, medics may combine ipratropium and albuterol for all three doses.

If 1 year or older, standing order

  • 0.5 mg mixed with 2.5 mg albuterol given via nebulizer over 5 - 15 minutes if the patient is not improving after a single albuterol-only nebulized treatment.
  • Medics may administer a second and third dose of 0.5 mg ipratropium mixed with 2.5 mg albuterol.
  • If status asthmatic is present, medics may combine ipratropium and albuterol for all three doses
Drug Action:
  • Bronchodilation
  • Dries respiratory tract secretions
Onset: 5-15 minutes
Duration: 4 - 6 hours
Indications:
  • Bronchospasm associated with asthma or COPD that does not respond to the first dose of albuterol
  • Bronchospasm from chemical toxins: nerve agents, cyanide, blistering agents, choking agents
Precautions: Notify BioTel (prior to administration) if patient has: Narrow-angle glaucoma, prostatic hypertrophy (enlarged prostate), bladder-neck obstruction
Side Effects:
  • Tachycardia/Palpitations
  • Restlessness/Nervousness
  • Blurred vision
  • Dizziness, Headache
  • Dry mouth
  • Cough, worsening of symptoms
  • Skin rash
Contraindications:
  • Sensitivity to soy lecithin products (soybeans, peanuts)
  • Sensitivity to Atropine
  • Bronchoconstriction that is caused by allergic reaction

 

 

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