Epinephrine 1:10,000

Adult Dose:

Cardiac arrest:

• 1mg push - standing order
  

Anaphylaxis:

• 0.1 mg - 0.2 mg slow push (over 1 minute) - standing order

Cardiac arrest:

• 0.01 mg/kg rapid push - standing order
  

Anaphylaxis:

• 0.01 mg/kg slow push (maximum is 0.3 mg per dose) - standing order

Alpha effects produce peripheral vasoconstriction which:

• Increases coronary and cerebral perfusion
  
• Increases blood pressure in anaphylaxis
  

Beta₁ effects:

• Increases heart rate
  
• Improves force of ventricular contractions
  

Beta₂ effects:

• Bronchodilation

• Cardiac arrest
  
• Anaphylaxis
  
• Pediatric bradycardia unresponsive to other treatment

CPR:

• None
  

Anaphylaxis:

• Monitor ECG closely
  
• Patients on beta-blockers may need glucagon or higher doses of epinephrine.
  
• Do not mix with sodium bicarbonate; flush tubing well between drugs.

CPR: None

Anaphylaxis:

• Tachycardia
  
• Ventricular arrhythmias
  
• Headache

• Flushing
  
• Nausea/vomiting
  
• Chest Pain