<--back to pharmacology table of contents
 

 

Dopamine HCL (Intropin®)

Class: Sympathomimetic
Route: IV or IO piggyback

Adult Dose:

2-10 mcg/kg/minute - BIOTEL AUTHORIZATION ONLY

  • 400 mg dopamine in 250 ml NS (1600 mcg/ml)
  • 800 mg dopamine in 500 ml NS (1600 mcg/ml)
Pediatric Dose:

2-10 mcg/kg/minute - BIOTEL AUTHORIZATION ONLy

  • 400 mg dopamine in 250 ml NS (1600 mcg/ml)
  • 800 mg dopamine in 500 ml NS (1600 mcg/ml)
Drug Action:
  • At low doses, increases perfusion to kidneys and abdominal organs
  • At moderate doses, increases force and rate of ventricular contraction
  • At high doses, peripheral vasoconstrictor
Onset: 2 minutes - 4 minutes
Duration: 10 minutes - 15 minutes
Indications:
  • Cardiogenic shock with systolic blood pressure between 70 mmHg – 90 mmHg
  • Symptomatic bradycardia unresponsive to atropine or TCP
Precautions:
  • Start IV’s in the antecubital fossa to lower risk of infiltration
  • Continually check IV site for patency and signs/symptoms of infiltration
  • Do not mix with sodium bicarbonate; flush tubing well between drugs
  • Continually monitor ECG, heart rate and blood pressure
Side Effects:
  • Tissue necrosis with infiltration
  • Hypertension
  • Tachycardia
  • Arrhythmias
Contraindications: Hypovolemic shock

 

 

<--back to pharmacology table of contents