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Diphenhydramine HCl (Benadryl®)

Class: Antihistamine
Route:
  • IV push (25mg/minute)
  • IM
  • IO (alternative route)

Adult Dose:

25mg - 50mg - standing order
Pediatric Dose: 1mg/kg - 2mg/kg - standing order
Drug Action:
  • Blocks histamine receptor sites in allergic reactions
  • Reverses side effects of dystonic reactions caused by phenothiazines
Onset: Maximum effects seen in 1 hour - 3 hours
Duration: 6 hours - 12 hours
Indications:
  • Allergic reactions - standing order
  • Dystonic reactions - BIOTEL AUTHORIZATION ONLY
Precautions: Acute asthma attack
Side Effects:
  • Drowsiness
  • Sedation
  • Disturbed coordination
  • Hypotension
  • Palpitations
  • Tachycardia
  • Bardycardia
  • Thickening of bronchial secretions
  • Dry mouth and throat
  • Paradoxical excitement in children
Contraindications: Hypersensitivity to diphenhydramine

 

 

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