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Allergic Reaction
Inclusion Criteria: Patients presenting with rash, hives, shortness of breath, or other signs and symptoms, up to and including shock, apparently due to an allergic reaction.
Basic Level
- Assess and support ABCs.
- Place the patient in a position of comfort. If evidence of shock, place the patient supine with the feet elevated.
- Isolate the patient from the source of the allergen, if possible.
- Administer oxygen, as needed to maintain an SpO2 of at least 96%
- Assess breath sounds. If wheezing is present and paramedics are not present at the scene, EMT-Basics may administer epinephrine via thepatient’s own autoinjector, if available. During injection, remember to hold the autoinjector against the patient’s skin for at least 10 seconds. EMT-Basics may not administer additional autoinjector doses of epinephrine without BioTel authorization.
Advanced Level
- Apply ECG and ETCO2 monitors if respiratory distress or shock is present or develops.
- Consider establishing IV access at a TKO rate or use a saline lock.
- Conditions:
| If localized reaction only (hives) administer: |
Adult
- diphenhydramine 25 mg - 50 mg IM or IV
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Pediatric
- diphenhydramine 1 mg/kg-2 mg/kg IM or IV
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| If dyspnea without shock, hypoperfusion, or critical airway, administer: |
Adult
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1:1,000 epinephrine 0.3 mg-0.5 mg SQ (unless given previously by autoinjector)
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diphenhydramine 25 mg – 50 mg IM or IV
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Pediatric
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1:1,000 epinephrine 0.01 mg/kg SQ (unless given previously by autoinjector) (max dose of 0.3mg)
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diphenhydramine 1 mg/kg-2 mg/kg IM or IV
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For bronchospasm unresponsive after 5 minutes to epinephrine SQ and diphenhydramine, administer albuterol 2.5 mg via nebulizer. May repeat for a total of three (3) doses. |
If shock, severe hypoperfusion, critical airway or SBP less than 90 mmHg, administer epinephrine 1:1,000 as soon as possible. Do not delay epinephrine administration while attempting IV/IO access. |
Adult
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1:1,000 epinephrine 0.3 mg-0.5 mg SQ. If the patient is responding but needs additional dose, repeat single dose every 20 minutes up to three doses (count autoinjector doses as part of the three)
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250 mL normal saline fluid boluses as needed (up to 1,000 mL) to maintain a systolic pressure of 90 mmHg
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diphenhydramine 25 mg - 50 mg IV/IO
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methylprednisolone 60 mg - 125 mg IVP (optional medication)
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If no response to the first SQ epinephrine and fluid bolus within 10 minutes, administer 1:10,000 epinephrine 0.1 mg - 0.2 mg IV or IO VERY SLOWLY (over 1 minute)
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Pediatric
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1:1,000 epinephrine 0.01 mg/kg SQ (max dose of 0.3mg)
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20 mL/kg normal saline fluid bolus
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diphenhydramine 1 mg/kg-2 mg/kg IM or IV/IO
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If no response to SQ epinephrine and fluid bolus within 10 minutes, administer 1:10,000 Epinephrine 0.01 mg/kg IV or IO
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For bronchospasm unresponsive after 5 minutes to epinephrine SQ and diphenhydramine, administer albuterol 2.5 mg via nebulizer. May repeat for a total of three (3) doses. |
- Monitor vital signs and transport
- For additional patient care considerations not covered under standing orders, consult BioTel.
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